Insider trading has been rife on Wall Street, academics conclude – In the know | The Economist

Source: Insider trading has been rife on Wall Street, academics conclude – In the know | The Economist

One study suggests insiders profited even from the global financial crisis; another that the whole share-trading system is rigged.

The papers make imaginative use of pattern analysis from data to find that insider trading is probably pervasive. The approach reflects a new way of analysing conduct in the financial markets. It also raises questions about how to treat behaviour if it is systemic rather than limited to the occasional rogue trader.

Why does drug resistance readily evolve but vaccine resistance does not? | The Royal Society

Source: Why does drug resistance readily evolve but vaccine resistance does not? | Proceedings of the Royal Society of London B: Biological Sciences, by David A. Kennedy, Andrew F. Read

Time to first detection of human pathogens resistant to vaccines and antimicrobial drugs. Viral vaccines are labelled in purple, bacterial vaccines are labelled in green. Blue ‘x’s denote the first observations of resistance, with lines starting at product introduction (except for smallpox vaccination which began much earlier). Note that in all cases, substantial public health gains continued to accrue beyond the initial appearance of resistance.

Why is drug resistance common and vaccine resistance rare? Drugs and vaccines both impose substantial pressure on pathogen populations to evolve resistance and indeed, drug resistance typically emerges soon after the introduction of a drug. But vaccine resistance has only rarely emerged. Using well-established principles of population genetics and evolutionary ecology, we argue that two key differences between vaccines and drugs explain why vaccines have so far proved more robust against evolution than drugs. First, vaccines tend to work prophylactically while drugs tend to work therapeutically. Second, vaccines tend to induce immune responses against multiple targets on a pathogen while drugs tend to target very few. Consequently, pathogen populations generate less variation for vaccine resistance than they do for drug resistance, and selection has fewer opportunities to act on that variation. When vaccine resistance has evolved, these generalities have been violated. With careful forethought, it may be possible to identify vaccines at risk of failure even before they are introduced.

Is the Universe a conscious mind? | Aeon Essays

Source: Is the Universe a conscious mind? | Aeon Essays, by Nigel Warburton

The subject matter of physics are the basic properties of the physics world: mass, charge, spin, distance, force. But the equations of physics do not explain what these properties are. They simply name them in order to assert equations between them. … physics is a tool for prediction.

Reflecting on the limitations of physics in The Nature of the Physical World (1928), Eddington argued that the only thing we really know about the nature of matter is that some of it has consciousness; we know this because we are directly aware of the consciousness of our own brains. … We have no direct access to the nature of matter outside of brains. But the most reasonable speculation, according to Eddington, is that the nature of matter outside of brains is continuous with the nature of matter inside of brains.

panpsychism: the view that all matter has a consciousness-involving nature.

There are two ways of developing the basic panpsychist position. One is micropsychism, the view that the smallest parts of the physical world have consciousness.

However, a number of scientists and philosophers of science have recently argued that this kind of ‘bottom-up’ picture of the Universe is outdated, and that contemporary physics suggests that in fact we live in a ‘top-down’ – or ‘holist’ – Universe, in which complex wholes are more fundamental than their parts.

If we combine holism with panpsychism, we get cosmopsychism: the view that the Universe is conscious, and that the consciousness of humans and animals is derived not from the consciousness of fundamental particles, but from the consciousness of the Universe itself.

The Crisis of American Forensics | The Nation

Source: The Crisis of American Forensics | The Nation, by Meehan Crist and Tim Requarth

Jimmy Genrich, and thousands of others, have been imprisoned for decades because of untested “science.” … By adopting the trappings of science, the forensic disciplines co-opted science’s authority while abandoning its methods.

“The legal concept of newly discovered evidence including a change in science,” says Chris Fabricant of the Innocence Project, who is litigating Genrich’s case, “is in my view a no-brainer. It was presented to a jury as infallible, and today we know it’s not. There is an obligation—an ethical, a legal, and a moral obligation—to go back and correct the record where exaggerated claims may have led to a miscarriage of justice.”

“We were really focused on ‘this isn’t a science.’ I can tell you from doing triple-digit jury trials, the jurors really want concrete evidence. Because it’s a very hard decision to make. And that’s why scientific evidence is so dangerous when it’s not a real science, because it is persuasive.”

Brainjunk and the killing of the internet mind | TechCrunch

Source: Brainjunk and the killing of the internet mind | TechCrunch, by Danny Crichton

Michael Pollan, the best-selling author of food books including the The Omnivore’s Dilemma and Food Rules, summarized his philosophy of eating quite simply. “Eat food. Not too much. Mostly plants.” The idea was to spend more on quality, and avoid the sorts of junk food that are deeply unhealthy for our physical bodies.

I think it’s well past time to borrow that philosophy for our brains. … So let me propose a little framework: “Enjoy content. Not too much. Mostly paid”.